The Database for Annotation, Visualization and Integrated Discovery (DAVID) provides a comprehensive set of functional annotation tools for investigators to understand the biological meaning behind large lists of genes. These tools are powered by the comprehensive DAVID Knowledgebase built upon the DAVID Gene concept which pulls together multiple sources of functional annotations. For any given gene list, DAVID tools are able to:

    Identify enriched biological themes, particularly GO terms
     Discover enriched functional-related gene groups
     Cluster redundant annotation terms
     Visualize genes on BioCarta & KEGG pathway maps
     Display related many-genes-to-many-terms on 2-D view.
     Search for other functionally related genes not in the list
     List interacting proteins
     Explore gene names in batch
     Link gene-disease associations
     Highlight protein functional domains and motifs
     Redirect to related literatures
     Convert gene identifiers from one type to another.
     And more

•   Multiple positions available in LHRI 
  The Laboratory of Human Retrovirology and Immunoinformatics (LHRI) has collaborated with the National Institute of Allergy and Infectious Diseases (NIAID) and supported NIAID clinical trials for patients infected with HIV mutants resisting anti-retroviral therapy. LHRI has isolated the multiple-class drug-resistant (MDR) variants from patients and characterized each variant's drug sensitivity and infectivity. The study aims to define salvage therapy and develop novel therapy (chemotherapy and immunotherapy). During the investigation, LHRI has characterized the emergence of novel mutations on drug susceptibility and viral replication. LHRI is a pioneer in researching the anti-viral cytokine, Interleukin-27, DNA-repair protein (Ku70)-mediated innate immune response against HIV and other virus co-infection, and novel subsets of immune cells. LHRI maintains the Database for Annotation, Visualization and Integrated Discovery ( DAVID ).
  
  

  (1) Postdoctoral Fellow position available to perform Microbiology/Cellular Immunology research in our Basic Research Section.

  (2) Postdoctoral Fellow, HIV Research position available to perform Microbiology/Cellular Immunology research in our Basic Research Section.

  (3) Computational Biologist position available to develop bioinformatics analysis pipelines and web-based bioinformatics applications in our Bioinformatics Section.

  (4) Bioinformatics Analyst position available to develop bioinformatics analysis pipelines and web-based bioinformatics applications in our Bioinformatics Section.

  
  
•  Call for papers 
  Submit papers for a Special Issue of Frontiers in Immunology: "IL-27 in Health and Disease"
  
• DAVID Forum
  Forum for DAVID users to ask questions, suggest new functions and help other users by answering their questions.
  
• FAQ
  Frequently Asked Questions
  
• LHRI Publications
  Publications of the Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research
  
• DAVID Publications
  Publications about DAVID
  

• December 2021
  DAVID 2021 Update released on our development site with DAVID Knowledgebase v2021q4.
• November 13, 2020
  Updated the DAVID header menu and home page.
• October 31, 2020
  DAVID v6.7 has been retired.
• October 28, 2020
  NEW Feature: Species selection feature added to List Upload and Conversion Tool when using Official Gene Symbol.
• September 1, 2020
  False discovery rate (FDR) has been changed from approximate FDR to adaptive FDR. Documentation for Benjamini and FDR has been updated.
• July 24, 2020
  The DAVID forum has been moved to https://david-bioinformatics.freeforums.net

• > 56K Citations (Updated 12/17/2021)
• Average Daily Usage: ~2,700 gene lists/sublists from ~900 unique researchers.
• Average Annual Usage: ~1,000,000 gene lists/sublists from >100 countries