The Database for Annotation, Visualization and Integrated Discovery (DAVID)
provides a comprehensive set of functional annotation tools for investigators to understand the biological meaning behind large lists of genes. These tools are powered by the comprehensive DAVID Knowledgebase built upon the DAVID Gene concept which pulls together multiple sources of functional annotations. For any given gene list, DAVID tools are able to:
Identify enriched biological themes, particularly GO terms
Discover enriched functional-related gene groups
Cluster redundant annotation terms
Visualize genes on BioCarta & KEGG pathway maps
Display related many-genes-to-many-terms on 2-D view.
Search for other functionally related genes not in the list
List interacting proteins
Explore gene names in batch
Link gene-disease associations
Highlight protein functional domains and motifs
Redirect to related literatures
Convert gene identifiers from one type to another.
- Multiple positions available in LHRI
The Laboratory of Human Retrovirology and Immunoinformatics (LHRI) has collaborated with the National Institute of Allergy and Infectious Diseases (NIAID) and supported NIAID clinical trials for patients infected with HIV mutants resisting anti-retroviral therapy. LHRI has isolated the multiple-class drug-resistant (MDR) variants from patients and characterized each variant's drug sensitivity and infectivity. The study aims to define salvage therapy and develop novel therapy (chemotherapy and immunotherapy). During the investigation, LHRI has characterized the emergence of novel mutations on drug susceptibility and viral replication. LHRI is a pioneer in researching the anti-viral cytokine, Interleukin-27, DNA-repair protein (Ku70)-mediated innate immune response against HIV and other virus co-infection, and novel subsets of immune cells. LHRI maintains the Database for Annotation, Visualization and Integrated Discovery ( DAVID ).
- Call for papers
Submit papers for a Special Issue of Frontiers in Immunology: "IL-27 in Health and Disease"
- DAVID Forum
Forum for DAVID users to ask questions, suggest new functions and help other users by answering their questions.
Frequently Asked Questions
- LHRI Publications
Publications of the Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research
- DAVID Publications
Publications about DAVID
DAVID 2021 Update released on our development site with DAVID Knowledgebase v2021q4.
November 13, 2020
Updated the DAVID header menu and home page.
October 31, 2020
DAVID v6.7 has been retired.
October 28, 2020
NEW Feature: Species selection feature added to List Upload and Conversion Tool when using Official Gene Symbol.
September 1, 2020
False discovery rate (FDR) has been changed from approximate FDR to adaptive FDR. Documentation for Benjamini and FDR has been updated.
July 24, 2020
The DAVID forum has been moved to https://david-bioinformatics.freeforums.net
- > 56K Citations (Updated 12/17/2021)
- Average Daily Usage: ~2,700 gene lists/sublists from ~900 unique researchers.
- Average Annual Usage: ~1,000,000 gene lists/sublists from >100 countries